Non-antigenic branched polymer conjugates

Details Non-antigenic branched polymer conjugates Non-antigenic branched polymer conjugates

1993-10-27

1997-07-01

Woodward, Michael P.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

4241781, 4241931, 42419511, 424 943, 530395, 5303911, 530402, 530408, 530409, 525 5411, A61K 39385, A61K 3854, C07K 1708, C08G 8300

Patent

active

056435754

ABSTRACT:
Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with the polymers and biologically active molecules such as proteins and peptides demonstrate extended circulating life in vivo. Substantially fewer sites on the biologically active material are used as attachment sites. Methods of forming the polymer, conjugating the polymers with biologically active moieties and methods of using the conjugates are also disclosed.

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