Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1983-11-22
1985-12-10
Lesmes, George F.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548221, C07D26358, A61K 3142
Patent
active
045580600
ABSTRACT:
The invention relates to compounds of the formula: ##STR1## in which R represents hydrogen or a lower alkyl radical and R.sub.1 and R.sub.2 separately represent hydrogen, a lower alkyl, cycloalkyl or benzyl radical, or represent, together with the nitrogen atom to which they are bonded, a heterocyclic radical such as a morpholino, 4-(pyrimidin-2-yl)-piperazinyl or 4-phenylpiperazinyl the phenyl radical of which being optionally substituted by halogen, lower alkoxy or trifluoromethyl, having CNS activity and particularly hypnotic properties.
Moreover the compounds in which R.sub.1 and R.sub.2 are hydrogen can be used in the treatment of heart failure.
Busch Norbert
Caignard Daniel H.
Lesieur Daniel
Lespagnol Charles
Gibson S. A.
Lesmes George F.
Riom Laboratories - Cerm S.A.
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