Substituted 1,4-dihydropyridines and their use as medicaments

Details Substituted 1,4-dihydropyridines and their use as medicaments Substituted 1,4-dihydropyridines and their use as medicaments

1983-12-09

1985-12-10

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546277, 546256, 546257, 546258, 546280, 514340, 514333, C07D41304, A61K 3144

Patent

active

045580588

ABSTRACT:
1,4-dihydropyridines of the formula I ##STR1## in which R denotes, for example, --CO.sub.2 R.sup.3 or cyano, R.sup.1 denotes, for example, an optionally substituted phenyl, pyridyl or thienyl, R.sup.2 denotes the radical of a 5-membered, optionally substituted, ring having at least one double bond and at least 2 heteroatoms or heteroatom groups from the series comprising O, N, NH and S, and R.sup.3 denotes, for example, alkyl or alkoxyalkyl, and their acid addition salts, have valuable pharmacological properties.

REFERENCES:
patent: 4144343 (1979-03-01), Baldwin
patent: 4145432 (1979-03-01), Sato
patent: 4260765 (1981-04-01), Harrison
patent: 4414213 (1983-11-01), Poindexter
Chemical Abstracts, vol. 93, No. 23, 220596j, 12/8/80, (Bayer).
Chemical Abstracts, vol. 94, No. 11, 83961d, 3/16/81, (Institute of Organic Synthesis).

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