Process for preparing spectinomycin analogs: N-demethylation of

Details Process for preparing spectinomycin analogs: N-demethylation of Process for preparing spectinomycin analogs: N-demethylation of

1981-10-16

1983-09-20

Love, Ethel G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D32304

Patent

active

044057970

ABSTRACT:
This invention is a novel chemical process particularly concerned with N-dealkylation of secondary amines as found in amino-cylitols of which spectinomycin is an example. Separation and further alkylation also comprise the present invention process.

REFERENCES:
patent: 3583972 (1971-06-01), Birkenmeyer et al.
patent: 4264776 (1981-04-01), Hershman et al.
Birkenmeyer et al, Tetrahedron Letters, No. 58, pp. 5049-5051, (1970).
Rosenbrook et al, ACS Symposium Series, No. 125, pp. 133-144, (1980).

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