A.T.C.C. HB8209 and its monoclonal antibody to erythropoietin

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 70, 4351722, 435948, 435803, 436518, 436548, 436817, 436824, 260112R, 935102, 935108, 935110, G01N 3354, C12N 1500, C12P 2102, C12R 191

Patent

active

045580065

ABSTRACT:
Disclosed is a new mouse-mouse hybridoma tumor cell line A.T.C.C. No. HB8209. A monoclonal antibody produced by said cell line is specifically immunologically reactive with erythropoietin and with a polypeptide whose amino acid sequence is substantially duplicative of a sequence extant is erythropoietin. Disclosed also are procedures for isolation of erythropoietin by affinity purification and for quantitative detection of erythropoietin in fluid samples.

REFERENCES:
patent: 3033753 (1962-05-01), White et al.
patent: 4376110 (1983-03-01), David et al.
patent: 4423147 (1983-12-01), Secher et al.
Lee-Huang, Fed. Proc., 41: 520 (1982).
Weiss et al, P.N.A.S., USA, 79: 5465-5469 (Sep. 1982).
Walter et al, P.N.A.S., USA, 78(8): 4882-4886 (1981).
Baron, Cell, 28: 395-404 (1982).
Chisholm, High Technology, 3(1): 57-63 (1983).
Cotes, Nature: 191: 1065-1067 (1961).
Dreesman, Nature, 295: 158-160 (1982).
Envall, J. Immunology, 109: 129 (1972).
Goding, J. Imm. Methods, 39: 285-308 (1980).
Green, Cell, 28: 477-487 (1982).
Hewick, J. Biol. Chem., 256: 7990-7997 (1981).
Hopp, PNAS, 78: 3824 (1981).
Kenneth, Monoclonal Antibodies: A New Dimension, p. 403 (1981).
Lerner, Cell, 23: 309-310 (1981).
Lerner, PNAS, 78: 3403-3407 (1981).
Lerner, Sci. Amer., 248(12): 66-74 (1983).
Merrifield, J. Amer. Chem. Soc., 85: 2149-2154 (1963).
Miyake, J. Biol. Chem., 252: 5558-5564 (1977).
Nigg, PNAS, 79: 5322-5326 (1982).
Oi, pp. 351-372, in Selected Methods Cell Immunology (1979).
O'Sullivan, Anal. Biochem., 100: 100-108 (1979).
Ross, Nature, 294: 654-656 (1981).
Shulman, et al., Nature, 276: 269 (1978).
Sevier, et al., Clin. Chem., 27(11): 1797-1806 (1981).
Walter, PNAS, 77: 5197-5200 (1980).
Wong, PNAS, 78: 7412-7416 (1981).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

A.T.C.C. HB8209 and its monoclonal antibody to erythropoietin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with A.T.C.C. HB8209 and its monoclonal antibody to erythropoietin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A.T.C.C. HB8209 and its monoclonal antibody to erythropoietin will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-58783

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.