Benzothiazine derivatives

Details Benzothiazine derivatives Benzothiazine derivatives

1981-12-11

1983-08-09

Ford, John M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 52, 544 2, 544 3, 544 5, 544 7, 544 8, C07D27916, C07D41712, A61K 3154

Patent

active

043978495

ABSTRACT:
This invention relates to novel benzothiazine derivatives having therapeutic effect on autoimmune diseases, to processes for preparation of such derivatives, and to pharmaceutical compositions containing such derivatives, the derivatives having the formula: ##STR1## wherein R.sup.1 is lower alkyl which may have one or more substituents selected from carboxy, aryl and carboxy(lower)cycloalkyl; aryl which may have one or more substituents selected from halogen, lower alkyl, halo(lower)alkyl and lower alkoxy; haloarylamino; or heterocyclic group;

REFERENCES:
patent: B348433 (1976-02-01), Krapcho
patent: 2863864 (1958-12-01), Kirchner
Journal of Heterocyclic Chemistry, vol. 16, (Dec. 1979), pp. 1503-1522; "Benzothiazinone Dioxides and Their Derivatives", Catsoulacos et al.

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