Process for the selective formation of dialkyl succinates

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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502171, 502230, 502313, 502326, 502331, 560190, C07C 6738

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active

048270237

ABSTRACT:
The invention discloses an improvement to the selective production of dialkyl succinates by the known process of oxidative carbonylation of an olefin with carbon monoxide, oxygen, and an alkyl alochol in the presence of a catalyst wherein the improvement comprises using a sulfone as the reaction solvent. The use of a sulfone, of which sulfolane is a preferred example, results in fast reaction rates and high selectivity to dialkyl succinates even in the absence of a dehydrating agent.

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Fenton et al., Chemtech, pp. 220-225, Apr. 1972.
James et al., Journal of the American Chemical Society, 98:7, pp. 1810-1823, Mar. 1976.
Stille et al., J. Org. Chem., vol. 44, No. 20, pp. 3474-3482, 1979.

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