Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-11-17
1989-05-02
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514912, A61K 3127
Patent
active
048268720
ABSTRACT:
The present invention relates to a treatment of cataract by administering a compound of the formula: ##STR1## wherein n is an integer of 8 to 20, and use thereof. The compound (I) of this invention has an excellent therapeutic effect against various types of cataract.
REFERENCES:
Chem. Abst.: 106:176,797m, (1987), Terao et al.
Chem. Abst.: 106:214301e, (1987), Terao et al.
Chem. Abst.: 108:118735v, (1988), Motoi.
Chem. Abst.: 108:150,870w, (1988), Kato et al.
Duncan, George, "Mechanisms of Cataract Formation in the Human Lens", 1981.
Bhuyan Kailash C. and Bhuyan, Durga K., "Molecular Mechanism of Cataractogenesis: III. Toxic Metabolites of Oxygen as Initiators of Lipid Peroxidation and Cataract", Current Eye Research, vol. 3, No. 1, 1984.
Azuma Mitsuyoshi
Terao Shinji
Watanabe Noriko
Robinson Douglas W.
Takeda Chemical Industries Ltd.
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