Non-optimal Kozaks sequences

Details Non-optimal Kozaks sequences Non-optimal Kozaks sequences

1998-10-06

2000-08-22

Zitomer, Stephanie W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 536 242, 4352523, 4353201, 435325, C07H 2104, C07H 2102, C12N 121, C12N 1579, C12N 1574

Patent

active

061074772

ABSTRACT:
A non-optimal translational start site (Kozak) polynuclcotide sequence as set forth in SEQ ID NO:2 is provided. An expression vector for expressing a protein of interest, utilizing the non-optimal translational start site is also provided. Host cells containing the expression vector utilizing the non-optimal translational start site are also provided. A selectable marker encoded by a nucleic acid sequences utilizing the non-optimal translational start site is further provided.

REFERENCES:
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Ryseck et al. Structure, mapping and expression of a growth factor inducible gene encoding a putative nuclear hormonal binding receptor. The EMBO Journal, vol. 8, pp. 3327-3335, Aug. 1989.
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