Thioalkylthio cephalosporin derivatives

Details Thioalkylthio cephalosporin derivatives Thioalkylthio cephalosporin derivatives

1993-03-02

1994-10-04

Morris, Patricia L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546276, 548110, C07D40106, C07D24904

Patent

active

053527925

ABSTRACT:
A novel thioalkylthio cephalosporin antibiotic compound of formula I: ##STR1## wherein Acyl is C.sub.1 -C.sub.12 acyl; Het is optionally substituted monocyclic heteroaromatic group containing one or more hetero atoms; R.sup.1 is a single bond or C.sub.1 -C.sub.4 alkylene; R.sub.2 is a straight or branched C.sub.1 -C.sub.4 alkylene; X is a sulfur atom or sulfoxide group; and Y is a hydrogen atom or methoxy group, or a pharmaceutically acceptable salt or an amino-, carboxy- and/or hydroxy-protected derivative thereof, a formulation containing the same and a method for treating bacterial infections.

REFERENCES:
patent: 3481946 (1969-12-01), Schmidt et al.
patent: 4482565 (1984-11-01), Foglio et al.

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