Thieno[3,2-b]pyridine derivatives

Details Thieno[3,2-b]pyridine derivatives Thieno[3,2-b]pyridine derivatives

1993-03-11

1994-10-04

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514183, 514214, 540477, 540582, 546114, A61K 31435, C07D49504

Patent

active

053526856

ABSTRACT:
The thieno[3.2-b]pyridine derivative of the present invention promote the gastric emptying in male ddy mice and the gastric contraction in dogs sutured with a strain-gauge transducer. It is believed that the derivatives have the action to enhance gastric motor action and gastric emptying. Therefore, the compound of the present invention are effective for the prevention and therapeutical treatment of the symptoms caused by gastric hypanakinesis, such as heartburn, abdominal distension feeling, anorexia, unpleasant feeling on upper abdomen, abdominalgia, nausea, vomiting, etc. caused by the underlying diseases such as acute and chronic gastritis, stomach and duodenum ulcer, gastroneurosis, gastroptosis, etc. The present invention also encompasses a pharmaceutical composition containing as the effective ingredient a compound of the present invention, and a method for producing the same.

REFERENCES:
patent: 4910193 (1990-03-01), Buchheit
patent: 5106851 (1992-04-01), Turconi et al.

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