Thiazolyl-substituted quinolylmethoxyphenylacetic acid derivativ

Details Thiazolyl-substituted quinolylmethoxyphenylacetic acid derivativ Thiazolyl-substituted quinolylmethoxyphenylacetic acid derivativ

1992-11-23

1994-02-01

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C07D41710, A61K 31425

Patent

active

052832520

ABSTRACT:
Thiazolyl-substituted quinolylmethoxyphenylacetic acid derivatives are prepared by reaction of halogenoacetoacetic acid esters with quinolylmethoxyphenylacetic acid thioamides, which are obtainable from corresponding amides with Lawesson's reagent. The substances can be employed in medicaments as inhibitors of enzymatic reactions in the context of arachidonic acid metabolism.

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