Process for the synthesis of pyrido-imidazo rifamycins

Details Process for the synthesis of pyrido-imidazo rifamycins Process for the synthesis of pyrido-imidazo rifamycins

1985-04-26

1985-12-10

Bond, Robert T.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D49122

Patent

active

045578664

ABSTRACT:
A new process for the synthesis of pyrido-imidazo-rifamycins of formula ##STR1## wherein R is hydrogen or acetyl, R.sub.1 and R.sub.2 independently represent hydrogen, (C.sub.1-4)-alkyl, benzyloxy, mono- or di-(C.sub.1-3)-alkylamino-(C.sub.1-4)-alkyl, (C.sub.1-3)-alkoxy-(C.sub.1-4)-alkyl, hydroxymethyl, hydroxy-(C.sub.2-4)-alkyl, cyano, halogen, nitro, mercapto, (C.sub.1-4)-alkylthio, phenylthio, carbamoyl, mono- or di-(C.sub.1-4)-alkyl-carbamoyl, or R.sub.1 and R.sub.2 taken together with two consecutive carbon atoms of the pyridine nucleus form a benzene ring optionally substituted by one or two methyl or ethyl groups.
The process comprises reacting the rifamycin O of formula ##STR2## with a 2-aminopyridine of formula ##STR3## wherein R.sub.1 and R.sub.2 have the same meanings as before.

REFERENCES:
patent: 4341785 (1982-07-01), Marchi et al.

Affiliated with

Also associated with

Rating

Process for the synthesis of pyrido-imidazo rifamycins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the synthesis of pyrido-imidazo rifamycins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the synthesis of pyrido-imidazo rifamycins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-57946