Pharmaceutical excipient having improved compressibility

Details Pharmaceutical excipient having improved compressibility Pharmaceutical excipient having improved compressibility

1998-03-10

2000-08-22

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424480, 424458, 424494, 424464, 424495, 424496, 424497, 424 49, 10615451, A61K 914

Patent

active

061068659

ABSTRACT:
A composition, comprising (a) microcrystalline cellulose; and (b) a compressibility augmenting agent which (i) physically restricts the proximity of the interface between adjacent cellulose surfaces; or (ii) inhibits interactions between adjacent cellulose surfaces; or (iii) accomplishes both (i) and (ii) above, is disclosed. The composition is in the form of agglomerated particles of microcrystalline cellulose and the compressibility augmenting agent in intimate association with each other.

REFERENCES:
patent: 4810516 (1989-03-01), Kong-Chan
patent: 5725884 (1998-03-01), Sherwood et al.
patent: 5733578 (1998-03-01), Hunter et al.
patent: 5858409 (1999-01-01), Karetney et al.
patent: 5858412 (1999-01-01), Staniforth et al.
patent: 5866166 (1999-02-01), Staniforth et al.

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