Substituted cyanoimino benzopyranes

Details Substituted cyanoimino benzopyranes Substituted cyanoimino benzopyranes

1991-08-15

1996-10-08

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514100, A61K 3135, A61K 3166, A61K 31665

Patent

active

055631703

ABSTRACT:
Novel compounds are disclosed having the formula ##STR1## and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are as defined herein. These compounds are useful, for example, as cardiovascular agents and especially as anti-ischemic agents.

REFERENCES:
V. A. Ashwood et al., J. Med. Chem., 1986, 29, 2194-2201.
A. Banerji et al., Tetrahedron Letters, No. 38, pp. 3685-3686 (1979).
J. M. Evans et al., J. Med. Chem., 1983, 26, 1582-1589.
R. W. Lang et al., Helvetica Chimica Acta., vol. 71 (1988) pp. 596-601.
G. Ariamala et al., Tetrahedron Letters, vol. 29, No. 28, pp. 3487-3488 (1988).
P. Sebok et al., Heterocycles, vol. 27, No. 11, 1988, pp. 2595-2607.
P. Teixidor et al., Heterocycles, vol. 27, No. 10 (1988) pp. 2459-2465.

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