Photostabilizing method for ophthalmic solutions and the resulti

Details Photostabilizing method for ophthalmic solutions and the resulti Photostabilizing method for ophthalmic solutions and the resulti

1992-07-31

1994-03-01

Fay, Zohreh A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514480, 514547, 514970, 514972, A61K 3155, A61K 3127, A61K 31225

Patent

active

052907740

ABSTRACT:
This invention relates to a photostabilizing method for ophthalmic solutions and the resulting ophthalmic solutions therefrom. The stabilization is attained by adding polyhydric alcohol and boric acid, and/or sodium borate to ophthalmic solutions which contain a drug substance unstable against light.

REFERENCES:
patent: 2455366 (1948-07-01), Rigby
patent: 3966905 (1976-06-01), Nite
patent: 4794177 (1988-12-01), Corbiere
7126297 Embase No.: 88123613 (1988) Asker et al.
Chemical Abst. 110(6): 141569u (1989) Ogata et al.
Asker et al., "Influence of Certain Additives on the Photostability of Physostigmine Sulfate Solutions", 14(5), 733-746, (1988) Drug Development and Industrial Pharmacy.

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