Compositions and methods employing liposomes including tyrosine

Details Compositions and methods employing liposomes including tyrosine Compositions and methods employing liposomes including tyrosine

1991-11-07

1994-03-01

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424 63, 424 70, 424401, 424417, 424420, 4284022, 514880, A61K 9127

Patent

active

052905624

ABSTRACT:
Compositions, for example cosmetic or pharmaceutical compositions, and methods of increasing melanin formation on the skin or scalp employ liposomes including between 0.001 and 10 weight percent, with respect to the total weight of the composition, of tyrosine or a tyrosine derivative selected from the group consisting of an alkali metal salt of L-tyrosine, an alkaline earth metal salt of L-tyrosine, methyl L-tyrosinate, ethyl L-tyrosinate, and stearyl L-tyrosinate.

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Mezei et al. Life Sciences-26, p. 1473 (1980).
Johsi et al, "Involvement of Reactive Oxygen Species in the Oxidation of Tyrosine and Dopa to Melanin and in Skin Tanning", Biochemical and Biophysical Research Communications, vol. 142, No. 1, Jan. 15, 1987, pp. 265-274.
Christine Jaworsky, M.D. et al., "Efficacy of tan accelerators," Journal of the American Academy of Dermatology, vol. 16, No. 4, 1987, pp. 769-771.

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