Pyridyl-substituted-benzofurans

Details Pyridyl-substituted-benzofurans Pyridyl-substituted-benzofurans

1982-09-30

1985-01-22

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546270, C07D40506

Patent

active

044953577

ABSTRACT:
The present invention provides novel pyridinyl-benzofurans and derivatives thereof which are useful as thromboxane A.sub.2 (TXA.sub.2) synthetase inhibitors and as such represent potent pharmacological agents.

REFERENCES:
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patent: 4271170 (1981-06-01), Tanouchi et al.
patent: 4410539 (1983-10-01), Cross et al.
Vernin et al., J. Heterocyclic Chem., vol. 16, pp. 97-103, Jan. 1979.
Takamatsu et al., J. C. S. Chem. Comm., pp. 903-904 (1973).
Benzofurans, Mustafa-Wiley (1974) p. 28.
Chem. Abstracts-Chem. Substance Index (1977-1981) pp. 8283 and 8284.
D. Harris, et al., Advances in Prostaglandin and Thromboxane Research 6:437 (1980).
T. Miyamoto, et al., Advances in Prostaglandin and Thromboxane Research 6:443 (1980).
H. Tai, et al., Advances in Prostaglandin and Thromboxane Research 6:447 (1980).

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