Process for producing and obtaining anaphylatoxin-and cocytotaxi

Details Process for producing and obtaining anaphylatoxin-and cocytotaxi Process for producing and obtaining anaphylatoxin-and cocytotaxi

1981-06-18

1985-01-22

Bleutge, John C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

435 68, 435 69, 424101, C07G 700

Patent

active

044950969

ABSTRACT:
The invention relates to a process for producing and obtaining anaphylatoxin- and cocytotaxin-containing leucotaxine preparations and anaphylatoxin and cocytotaxin proteins in molecularly homogeneous, biologically active form from contact-activated mammalian serum by the following steps:

REFERENCES:
Tack, B. F. et al., Biochemistry, vol. 15, No. 20, pp. 4513-4521, 1976.
Wissler, J., Eur. J. Immunol. vol. 2, pp. 73-96, 1972.
Vallota, E., J. Exp. Med., vol. 137, pp. 1109-1123, 1973.
Gerard, C., J. Biol. Chem., vol. 254, pp. 6346-6351, 1979.
Conroy, M., J. Immunol., vol. 116, pp. 1682-1687, 1976.
Fernandez, H., J. Immunol., vol. 120, pp. 109-115, 1978.

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