Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleo

Details Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleo Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleo

1995-02-02

1996-11-12

Robinson, Douglas W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2855, 536124, C07H 19067, C07H 19073

Patent

active

055741487

ABSTRACT:
A method of making a radiolabeled pyrimidine nucleoside or nucleotide is described. In the method an aqueous solution (i) a radioactive iodide, bromide, chlorine or astatide ion and (ii) a water soluble halomercuri pyrimidine nucleoside or nucleotide is contacted with an oxidizing agent, whereby a water soluble pyrimidine nucleoside or nucleotide labeled with radioactive iodine, bromine, chlorine or astatine is formed. Kits suitable for practicing the method are also disclosed.

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