Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-04-08
2000-01-18
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514212, 514216, 514299, 514305, 514362, 514342, 544333, 546112, 546133, 5462687, 540593, 540601, 540603, 548135, A61K 31505, A61K 31445, C07D41714
Patent
active
060158131
ABSTRACT:
The present invention relates to therapeutically active azabicyclic compounds of formula I ##STR1## wherein X, R.sup.1, R.sup.2, R.sup.3, Ar, m and n are defined in the description, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating a disease in the central nervous system caused by malfunctioning of the muscarinic cholinergic system.
REFERENCES:
patent: 5527813 (1996-06-01), Sauerberg et al.
patent: 5914338 (1999-06-01), Jeppesen et al.
Ward et al., "Novel Functional M1 Selective Muscarinic Agonists," J. Med. Chem., vol. 35, pp. 4011-4019, 1992.
Levine, "Controlled Trials of Inositol in Psychiatry," Eur. Neuropsychopharmacology, vol. 7, No. 2, MEDLINE abstract, May 1997.
Jeppesen Lone
Sauerberg Per
Kessinger Ann M.
Novo Nordisk A S
Rozek Carol E.
Shah Mukund J.
Zelson Steve T.
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