Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1995-02-22
1996-11-12
Ulm, John
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
514 2, 514 12, 424 852, 435 6952, A61K 3820, C07K 1454
Patent
active
055741380
ABSTRACT:
Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for treating or preventing gastrointestinal diseases and HIV or HIV-associated diseases.
REFERENCES:
Grabstein et al., "Cloning of a T Cell Growth Factor That Interacts with the .beta. Chain of the Interleukin-2 Receptor," Science 264:965-968, 1994.
McMahan et al., "A Novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types," EMBO Journal 10(10): 2821-2832, 1991.
Anderson Dirk M.
Eisenman June R.
Fung Victor
Grabstein Kenneth H.
Rauch Charles
Immunex Corporation
Malaska Stephen L.
McMasters David M.
Mertz Prema
Ulm John
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