Methods of treatment using 2',3'-dideoxy-2',2'-difluoronucleosid

Details Methods of treatment using 2',3'-dideoxy-2',2'-difluoronucleosid Methods of treatment using 2',3'-dideoxy-2',2'-difluoronucleosid

1995-06-02

1996-11-12

Wilson, James O.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 46, 514 49, 514 50, 514908, 536 2714, 536 282, A61K 3170

Patent

active

055740219

ABSTRACT:
2',3'-Dideoxy-2',2'-difluoronucleosides are useful for treating susceptible neoplasms and viral infections in mammals.

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patent: 4880782 (1989-11-01), Eckstein et al.
patent: 4908440 (1990-03-01), Sterzicki et al.
Herdewijn et al., "Synthesis . . . Analysis", J. Med. Chem, vol. 30, pp. 2131-2137 (1987).
Bergstrom et al. "Abstract presented at Spring 1983 ACS Meeting" in Seattle.
Wright and Taylor, Carbohydrate Res. 6, 347-54 (1968).
C. A. Abstract 109:222451f (1989).
The New England Journal of Medicine, vol. 316, No. 9, 26 Feb. 1987, "Development of Antiretroviral Therapy For The Acquired Immunodeficiancy Syndrome and Related Disorders", Yarchoan, et al.

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