Process for preparing mixtures containing 8,9-epithio-1-p-menthe

Details Process for preparing mixtures containing 8,9-epithio-1-p-menthe Process for preparing mixtures containing 8,9-epithio-1-p-menthe

1983-08-01

1985-08-20

Sutto, Anton H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

252522R, C07D33102, A61K 746

Patent

active

045365830

ABSTRACT:
Described is a process for preparing a mixture of t-mercapto terpenes defined according to the structure: ##STR1## and .alpha.-terpineol defined according to the structure: ##STR2## including the step of reacting the compound defined according to the structure: ##STR3## with an alkali metal thiocyanate defined according to the structure: ##STR4## wherein M represents alkali metal such as sodium, potassium or lithium in the presence of a phase transfer catalyst. The resulting product is then treated with lithium aluminum hydride followed by aqueous mineral acid to form a mixture of .alpha.-terpineol and the compound defined according to the structure: ##STR5## which mixture is useful for its organoleptic properties.

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