Polyphosphazene polyelectrolyte immunoadjuvants

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector

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Details

4242801, 424 111, 514110, 514114, 514 75, 514137, A61K 3900, A61K 4500, A61K 5100

Patent

active

060155639

ABSTRACT:
A polyphosphazene polyelectrolyte immunoadjuvant having improved water solubility, a vaccine composition of the immunoadjuvant and an antigen or immunogen and methods of their use in producing or enhancing an immunoprotective response in a host are disclosed.

REFERENCES:
patent: 5284934 (1994-02-01), Allen, Jr.
patent: 5494673 (1996-02-01), Adrianov et al.
patent: 5855895 (1999-01-01), Andrianov et al.
Cohen, et al., J. Am. Chem. Soc., vol. 112, pp. 7832-7833 (1990).
Andrianov, et al., J. Controlled Release, vol. 27, pp. 69-77 (1993).

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