Process for microbial transformation of steroids

Details Process for microbial transformation of steroids Process for microbial transformation of steroids

1978-11-20

1980-07-08

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435172, C12P 740

Patent

active

042118417

ABSTRACT:
Novel microbial transformation process to selectively convert steroids with or without 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to 3a.alpha.-H-4.alpha.-[3'-propionic acid]-7a.beta.-methylhexahydro-1,5-indanedione having the following structure: ##STR1## This compound can be used as an intermediate to make useful 19-nor steroids.

REFERENCES:
patent: 2602769 (1952-07-01), Murray et al.
patent: 3684657 (1972-08-01), Kraychy et al.
patent: 3759791 (1973-09-01), Marsheck et al.
patent: 4062729 (1977-12-01), Biggs et al.
Wang et al, Biochemistry, vol. 2, No. 6, pp. 1238-1243 (1963).
Mamoli et al., Ber. 70, 470 & 471, 2079-2082 (1937).
Sih et al., J. Am. Chem. Soc. 85: 2135-2137 (1963).
Schubert et al., Steroids 4: 581-586 (1964).

Affiliated with

Also associated with

Rating

Process for microbial transformation of steroids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for microbial transformation of steroids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for microbial transformation of steroids will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-560930