2-Methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole

Details 2-Methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole 2-Methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole

1979-04-17

1981-04-21

Daus, Donald G.

Harness for working animal

424270, C07D28512, A61K 31424

Patent

active

042634300

ABSTRACT:
2-Methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole of the formula ##STR1## and processes for its preparation by condensing salicylaldehyde with 2,5-dimethyl-1,3,4-thiadiazole or 2-methyl-5-(triphenylphosphine-methylene)-1,3,4-thiadiazole. 2-Methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole is a valuable intermediate for the preparation of pharmacologically active compounds; for example the alkylamino-hydroxypropyl ethers can, because of their .beta.-sympatholytic action, be used as drugs for the treatment of coronary diseases of the heart, cardiac arrhythmias and hypertonia.

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