N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids and de

Details N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids and de N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids and de

1983-05-26

1985-06-25

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514422, 514414, 548465, 548467, 548518, 548550, 546208, C07D40306, C07D40106, C07D20709, A61K 3140

Patent

active

045254761

ABSTRACT:
N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids, base addition salts, esters, and amides are useful as cognition activators. Pharmaceutical compositions containing these compounds and methods of using the pharmaceutical compositions for treating senility or amnesia are also disclosed.

REFERENCES:
patent: 3459738 (1969-08-01), Morren et al.
patent: 4144246 (1979-03-01), L'Italien et al.
patent: 4145347 (1979-03-01), L'Italien et al.
patent: 4372966 (1983-02-01), Butler
Colonge et al., Bul. Soc. Chim. France, vol. 3, (1962), pp. 598-603.
Leonard et al., J. Am. Chem. Soc., vol. 69, (1947), pp. 690-692.

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