Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1981-05-08
1982-06-08
Shapiro, Lionel M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435253, 435896, C12P 1962, C12N 120
Patent
active
043340199
ABSTRACT:
23-De(mycinosyloxy)tylosin (DMOT) which has the formula: ##STR1## 20-dihydro-DMOT, specified acyl ester derivatives, and the acid addition salts thereof are useful antibacterial agents. New methods of making 23-deoxy-5-O-mycaminosyltylonolide (DOMT) and 20-dihydro-DOMT by mild acid hydrolysis of DMOT and 20-dihydro-DMOT, respectively, are included.
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Baltz Richard H.
Seno Eugene T.
Wild Gene M.
Eli Lilly and Company
Harrison Nancy J.
Shapiro Lionel M.
Whale Arthur R.
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