Process for preparing indole derivatives

Details Process for preparing indole derivatives Process for preparing indole derivatives

1976-03-23

1977-03-29

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260315, 2603191, 26032615, 26032616, 26032682, 260295C, 2602948B, 26032631, 2603131, C07D47104

Patent

active

040148904

ABSTRACT:
Certain indole derivatives, and especially certain 1,2,3,4-tetrahydrocarbazoles, 1,2,3,4-tetrahydro-.gamma.-carbolines and 1,2,3,4-tetrahydropyrrolo-[3,4-b]indoles are prepared by reacting the appropriate phenylhydrazine salt and ketone in the presence of a weakly basic solvent such as pyridine, quinoline, N,N-dimethylaniline, picoline or lutidine at a temperature in the range of about 50.degree. to 180.degree. C.

REFERENCES:
patent: 3535326 (1970-10-01), Yamamoto et al.
Posvic et al. "J. Org. Chem.," vol. 39 pp. 2575-2580 (1974).

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