Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-01-27
1977-03-29
Rizzo, Nicholas S.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07D50106
Patent
active
040148742
ABSTRACT:
The invention concerns a new process for the manufacture of 3-substituted thiomethyl-7-amino-3-cephem-4-carboxylic acid compounds which comprises reacting a 3-y-methyl-7-amino-3-cephem-4-carboxylic acid compound, in which Y is hydroxy or esterified hydroxy, with a mercaptane compound, if necessary, in the presence of an optionally protonic Lewis acid, particularly trifluoroacetic acid.
REFERENCES:
patent: 3867380 (1975-02-01), Dunn et al.
patent: 3878204 (1975-04-01), Ochiai et al.
patent: 3891629 (1975-06-01), Diassi et al.
patent: 3948905 (1976-04-01), De Marinis et al.
patent: 3965099 (1976-06-01), De Marinis et al.
patent: 3975385 (1976-08-01), Bouchaudon et al.
Bickel Hans
Muller Beat
Peter Heinrich
Sibral Walter
Ciba-Geigy Corporation
Groeger Theodore O.
Kolodny Joseph G.
Maitner John J.
Rizzo Nicholas S.
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