Preparation of .beta.-lactam antibiotics

Details Preparation of .beta.-lactam antibiotics Preparation of .beta.-lactam antibiotics

1975-09-02

1977-03-29

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260243C, C07D49968

Patent

active

040148688

ABSTRACT:
The sodium salt of amoxycillin or other .beta.-lactam antibiotic is prepared by slurrying the antibiotic in zwitterionic form in a lower alkanol-containing organic solvent system, causing dissolution of the antibiotic by adding a sodium hydroxide or lower alkoxide, precipitating the resulting salt by adding an organic solvent and isolating the precipitate.

REFERENCES:
patent: R28744 (1976-03-01), Long et al.

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