Method for reducing gamma radiation sterilization induced discol

Details Method for reducing gamma radiation sterilization induced discol Method for reducing gamma radiation sterilization induced discol

1995-05-31

1996-10-08

Prebilic, Paul B.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Bone

623 11, 623901, 128898, 4332011, A61F 228

Patent

active

055627340

ABSTRACT:
A method for chemically extracting the low-molecular weight chemical additives from a polymethylmethacrylate coating formed on an orthopaedic implant. Specifically, the implant is subjected to a solvent extraction process to remove residual N,N,-dimethyl-p-toluidine, hydroquinone, and methyl methacrylate monomer from the polymethylmethacrylate mass. A solvent such as methanol or hot water does not attack the polymethylmethacrylate but effectively diffuses into the polymethylmethacrylate to extract out these unreacted and residual components. The removal of these components substantially inhibits discoloration and random chain scission in polymethylmethacrylate upon subsequent irradiation for sterilization purposes.

REFERENCES:
patent: 4172702 (1979-10-01), Bernier et al.
patent: 4281420 (1981-08-01), Raab
patent: 4283799 (1981-08-01), Pratt, Jr. et al.
patent: 4336618 (1982-06-01), Raab
patent: 4341691 (1982-07-01), Anuta
patent: 4491987 (1985-01-01), Park
patent: 4547327 (1985-10-01), Bruins et al.
patent: 4636212 (1987-01-01), Posin et al.
patent: 4820755 (1989-04-01), Webster
patent: 4881536 (1989-11-01), Noble et al.
patent: 5037445 (1991-08-01), Sander et al.
patent: 5080680 (1992-01-01), Mikhail et al.
patent: 5116380 (1992-05-01), Hewka et al.
patent: 5133771 (1992-07-01), Duncan et al.
patent: 5331043 (1994-07-01), Koch et al.
patent: 5472415 (1995-12-01), King et al.
Howmedica, Inc.-Precision Strata Hip System-JBJS, Dec. 1993.
Zimmer, Inc.-Harris Precoat Plus Hip Prosthesis-1988.
Zimmer, Inc.-Cement Centralizer Use Review-1992.

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