Intranasally applicable powdery pharmaceutical composition

Drug – bio-affecting and body treating compositions – Lymphokine – Interferon

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424 858, 514 2, 514 3, 514 11, 514 12, A61K 3766, A61K 3900, A61K 3700, A61K 3726

Patent

active

049852426

ABSTRACT:
An intranasally applicable powdery pharmaceutical composition comprising a polypeptide having a physiological activity, a quaternary ammonium compound, and a lower alkyl ether of cellulose. This powdery pharmaceutical composition has an excellent preservability and chemical stability of the polypeptides and, when the powdery composition is administered to the nasal cavity in the form of a spray, the polypeptides are effectively absorbed through the nasal mucosa.

REFERENCES:
patent: 4613500 (1986-09-01), Suzuki et al.
S. Hirai et al, Diabetes vol. 27, p. 296, (1978).

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