Thioheterocyclic near-infrared absorbing dyes

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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544298, 544315, 544318, 544345, 546256, 546266, 548142, 548159, 548215, 548221, 548251, 5482632, 5482634, 5482648, C07D26308, C07D26302, C07D24912, C07D24908

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active

055764436

ABSTRACT:
Disclosed is a novel near-infrared absorbing dye of formula: ##STR1## wherein X.sup.1, X.sup.2 independently represents --CR.sup.8 R.sup.9 --, --S--, --Se--, --NR.sup.10 --, --CH.dbd.CH-- or --O--;

REFERENCES:
patent: 4882265 (1989-11-01), Laganis et al.
Slominskii et al CA 91:22390, 1979.
L. Strekowski et al., Facile Derivatizations of Heptamethine Cyanine Dyes, Synthetic Communications, 22(17), pp. 2593-2598, 1992.
L. Strekowski et al., Substitution Reactions of a Nucleofugal Group in Heptamethine Cyanine Dyes. Synthesis of an Isothiocyanato Derivative for Labeling of Proteins with a Near-Infrared Chromophore, J. Org. Chem., 57, pp. 4578-4580, 1992.
R. J. Williams, et al., Comparison of Covalent and Noncovalent Labeling with Near-Infrared Dyes for the High-Performance Liquid Chromatographic Determination of Human Serum Albumin, Anal. Chem., vol. 65, pp. 601-605, 1993.

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