Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-12-09
1992-01-14
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514418, 514419, 548253, 548484, 548492, C07D40312, C07D20910, A61K 3141, A61K 3140, A61K 31405
Patent
active
050811380
ABSTRACT:
Compounds having the formula: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
REFERENCES:
patent: 3198807 (1965-08-01), Thominet
patent: 3502667 (1970-03-01), Makenishi
patent: 4654360 (1987-03-01), Greenhouse et al.
patent: 4876246 (1989-10-01), Guindon et al.
Fortin Rejean
Gillard John W.
Guindon Yvan
Morton Howard E.
DiPrima Joseph F.
Lopez Gabriel
Merck Frosst Canada Inc.
Springer David B.
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