Method of treating cancer using structured lipids

Details Method of treating cancer using structured lipids Method of treating cancer using structured lipids

1990-01-25

1992-01-14

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514549, 514552, A61K 3700, A61K 3122, A61K 3123

Patent

active

050811053

ABSTRACT:
Disclosed is a method of treating cancer using nutritional support therapy by administration of a structured lipid containing both .omega.3 fatty acids and medium-chain fatty acids. The therapy may be used as total parenteral nutrition or as a nutritional supplement. The addition of tumor necrosis factor may also be beneficial.

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patent: 4703062 (1987-10-01), Blackburn et al.
patent: 4906664 (1990-03-01), Bistrian et al.
The Handbook of Chemistry and Physics, 57th ed., CRC Press, pp. D216-217, Weast, Ed.
"Fish Oil Slows Tumor Growth and Prolongs Survival in a Transplantable Metastatic Breast Cancer Model", (ABSTRACT) Szeluga et al., Metabolism Lab., NEDH, Harvard Medical School, Boston, Mass.
"Medium-chain triglycerides: an update", Bach and Babayan, Amer. J. of Clin. Nut., 36:Nov. 1982, pp. 950-962.
"Improved protein kinetics and albumin synthesis by branched chain amino acid-enriched total parenteral nutrition in cancer cachexia", Tayek et al., CANCER 58:No 1, Jul. 1, 1986.
"Some practical and theoretic concepts in the nutritional assessment of the cancer patient", Bistrian, CANCER, 58:No. 8, Oct. 15, 1986.
"Effect of total enteral nutrition with structured lipid on protein metabolism in thermally injured rats", DeMichele et al., Fed. Proc., 46:1086 (1987).

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