Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-31
1996-11-19
Dentz, Bernard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514415, 514470, 514534, 546158, 548481, 549467, 549471, 560 42, A61K 31215, C07C 69616
Patent
active
055763324
ABSTRACT:
New soft .beta.-adrenergic blocking agents, useful in the treatment or prevention of cardiovascular disorders and in the treatment of glaucoma, have the formula ##STR1## wherein n is an integer from 0 to 10; R is C.sub.6 -C.sub.12 cycloalkyl-C.sub.p H.sub.2p --, C.sub.6 -C.sub.18 polycycloalkyl-C.sub.p H.sub.2p --, C.sub.6 -C.sub.18 polycycloalkenyl-C.sub.p H.sub.2p -- or C.sub.6 -C.sub.12 cycloalkenyl-C.sub.p H.sub.2p -- (wherein p is 0, 1, 2 or 3), or together with the adjacent ##STR2## group represents a variety of other complex ester groupings; R.sub.1 is C.sub.1 -C.sub.7 alkyl; and Ar is a divalent radical containing at least one aromatic nucleus. The corresponding pharmaceutically acceptable acid addition salts are also described.
REFERENCES:
patent: 3663607 (1972-05-01), Barrett et al.
patent: 3836671 (1974-09-01), Barrett et al.
patent: 4287194 (1981-09-01), Kosa et al.
patent: 4387103 (1983-06-01), Erhardt et al.
patent: 4438128 (1984-03-01), Wiedemann et al.
patent: 4454154 (1984-06-01), Matier
patent: 4578403 (1986-03-01), Matier
patent: 4703057 (1987-10-01), Marchand et al.
Bodor et al, Pharmaceutical Research, 1984, No. 3, 120-125.
Erhardt et al, J. Med. Chem., 1982, vol. 25, No. 12, 1408-1412.
LandOfFree
Soft .beta.-drenegic blocking agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Soft .beta.-drenegic blocking agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Soft .beta.-drenegic blocking agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-541292