Indolyl derivatives and their use as 5-HT.sub.3, receptor antago

Details Indolyl derivatives and their use as 5-HT.sub.3, receptor antago Indolyl derivatives and their use as 5-HT.sub.3, receptor antago

1989-07-12

1991-09-10

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514210, 514212, 514339, 514419, 514311, 514342, 514314, 514343, 514346, 514350, 514359, 514406, 514428, 514443, 514521, 514523, 514534, 514535, 514540, 514617, 514618, 514619, 514621, 514622, 540480, 540602, 548492, 548259, 548359, 548569, 546112, 546183, 546273, 546156, 546169, 546170, 546275, 546291, 546298, 546316, 546318, 560 12, 560 13, 560 20, 560 22, 560 23, 560 37, 560 38, 560 39, 560 41, 564162, 564163, 564166, 564167, 564169, 564170, 564176, 564183, 564186, A61K 31165, A61K 31235, A61K 31275, A61K

Patent

active

050474103

ABSTRACT:
New pharmacologically active amidino and guanidino derivatives which are 5-HT.sub.3 receptor antagonists useful as antiemetic, gastric prokinetic and antimigrainic agents of the following general formula (I) ##STR1## , wherein the substituents are defined hereinbelow, which compounds are 5-HT.sub.3 receptor antagonists useful as antiemetic gastric prokinetic and antimigraine agents, inter alia.

REFERENCES:
patent: 4814345 (1989-04-01), Ohlendorf et al.

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