Methods of treating angiogenesis-induced diseases and pharmaceut

Details Methods of treating angiogenesis-induced diseases and pharmaceut Methods of treating angiogenesis-induced diseases and pharmaceut

1995-05-31

2000-07-11

Cunningham, Thomas M.

Drug, bio-affecting and body treating compositions

Lymphokine

424 856, 424 857, A61K 3819, A61K 31335

Patent

active

060868651

ABSTRACT:
The present invention provides for the use of fumagillin or an O-substituted fumagillol derivative in conjunction with interferon which increases the angiogenic inhibitory action as compared with the agents administered alone. It has also been discovered that in the treatment of certain angiogenesis-induced diseases, the combination of the present invention is synergistic in angiogenesis inhibitory effect. The invention further provides a method for treatment of angiogenesis-induced diseases.

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