Mass spectrometry method using supplemental AC voltage signals

Details Mass spectrometry method using supplemental AC voltage signals Mass spectrometry method using supplemental AC voltage signals

1991-08-30

1993-04-06

Berman, Jack I.

Radiant energy

Ionic separation or analysis

Methods

250291, 250292, H01J 4942

Patent

active

052006131

ABSTRACT:
A mass spectrometry method in which a supplemental AC voltage signal having at least one high power frequency component, and at least one low power frequency component, is applied to an ion trap. Each high power component has an amplitude sufficiently large to eject one or more selected ions from the trap, by resonantly exciting the ions. Each low power component has an amplitude sufficient to induce dissociation (or reaction) of one or more selected ions, but insufficient to resonate the ions for detection. The frequency (or band of frequencies) of each high and low power frequency component is selected to match a resonance frequency of ions having a desired mass-to-charge ratio. Each low power component is applied for the purpose of inducing dissociation or reaction of specific trapped ions, which may be parent, daughter, reagent, or product ions, and each high power component is applied to eject undesired products of each such dissociation or reaction process from the trap. In accordance with the invention, a supplemental voltage signal having appropriately selected high and low power frequency components is applied to a trap during an (MS).sup.n or CI, or combined CI/(MS).sup.n, mass spectrometry operation.

REFERENCES:
patent: 4540884 (1985-09-01), Stafford et al.
patent: 4686367 (1987-08-01), Louris et al.
patent: 4736101 (1988-04-01), Syka et al.
patent: 4749860 (1988-06-01), Kelley et al.
patent: 4761545 (1988-08-01), Marshall et al.
patent: 4882484 (1989-11-01), Franzen et al.
patent: 4975577 (1990-12-01), Franzen et al.
patent: 5075547 (1991-12-01), Johnson et al.
patent: 5134286 (1992-07-01), Kelley
Extension of Dynamic Range in Fourier Transform Ion Cyclotron Resonance Mass Spectrometry via Stored Waveform Inverse Fourier Transform Excitation, Tao-Chin Lin Wang, Tom L. Ricca & Alan Marshall, Anal. Chem., 1986, 5B, 2935-2938.
P. H. Dawson & N. R. Whetten, "Non-Linear Resonances in Quatrupole Mass Spectrometers Due to Imperfect Fields I. The Quadrupole Ion Trap," J. Mass Spectrometry and Ion Physics, vol. 2, 1969, pp. 45-59.

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