Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-05-30
1997-04-01
Patterson, Jr., Charles L.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 4353201, 514 12, 530326, 530412, 530416, 530418, 536 221, 536 235, C12P 2106, A61K 3800, C07H 1900, C12N 500
Patent
active
056164769
ABSTRACT:
The invention relates to novel synthetic isohirudins which have improved stability owing to exchange in the region of the Asp-Gly motif. This results, on the one hand, in an increase in the yield during workup and, on the other hand, in making possible pharmaceutical formulation as directly injectable solution ready for use.
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Crause Peter
Habermann Paul
Schmid Gerhard
Tripier Dominique
Ulmer Wolfgang
Hoechst Aktiengesellschaft
Kim Hyosuk
Patterson Jr. Charles L.
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