Process for the production of 2-azabicyclo [2.2.1] hept-5-en-3-o

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548543, 548552, 548553, C07D20952

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active

052005275

ABSTRACT:
2-Azabicyclo[2.2.1]hept-5-en-3-one is produced by Diels-Alder reaction of cyclopentadiene and methanesulfonyl cyanide and then hydrolytic cleavage of the methanesulfonyl group.

REFERENCES:
patent: 4118393 (1978-10-01), Faushawe et al.
Chemical Abstracts, vol. 111, No. 5, Jul. 31, 1989), Abstract No. 111: 39161p.
J. C. Jagt and A. M. van Larsen, J. Org. Chem., vol. 39, (1974), pp. 564 to 566.
S. Daluge and R. Vince, vol. 43, No. 12, (Jun. 9, 1978), pp. 2311 to 2320).
J. R. Malpass and N. J. Tweddle, vol. 1977, No. 8, (1977), J. Chem. Soc., Perkin I, pp. 874 to 884.
M. S. A. Vrijland, Org. Synth., Coll. vol. VI, pp. 727 to 730 (1970).

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