Polypeptide propoxyphene derivatives for immunoassay reagents

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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23230B, 195 63, 195 68, 1951035R, 260112R, 260112B, 260 78A, 260463, 2605705R, 260576, 424 12, 424 85, 424 88, C07G 700

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active

040255018

ABSTRACT:
Novel compounds are provided which are derivatives of 1,2-diphenyl-3-methyl-4-dimethylamino-2-butanol. The indicated alcohol is employed to prepare the monoester of a dibasic acid which is conjugated with an antigen for the production of antibodies which recognize both propoxyphene and its N-desmethyl metabolite in immunoassays.

REFERENCES:
patent: 3690834 (1972-09-01), Goldstein et al.
patent: 3817837 (1974-06-01), Rubenstein et al.
patent: 3852157 (1974-12-01), Rubenstein et al.
J. Am. Chem. Soc. 75, 4458-4461, (1953), Pottland et al.

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