Process for the preparation of extracts having high content in a

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex

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8646, 514456, A61K 3578, A61K 3135, C09B 6100

Patent

active

052001865

ABSTRACT:
A process for the preparation of extracts with high content in anthocyanosides consists in treating plants, parts of plants or crude extracts with bisulfite ions to give anthocyanoside-bisulfite adducts. Said adducts are then eluted on non ionogenic resins at pH 5-6 and the obtained solution is extracted with polar organic solvents immiscible in water. The obtained extracts have a constant and standardized composition in anthocyanosides.

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Steinmetz E. F. 1957 Codex Vegetabilis Amsterdam #972, #1016, #1178, #1206.
Martinelli E. M. Computer Aided Evaluation of . . . Anthocyanins, Analytica Chimica Acta 191 (1986) pp. 275-281.
Colantuoni A., Effects of V. myrtillus Anthocyanosides on Arterial Vasomotion, Drug Res. 41(11)9, 905-909 (1991).
"The Flavonoids", edited by J. B. Harborne, T. J. Mabry, Helga Mabry Chapman and Hall, London, p. 227.

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