Process for the preparation of metal complexes of isoindolinazin

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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546 7, 548105, 548106, 548403, 106288Q, C07F 1500, C09B 5704

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active

044749520

ABSTRACT:
Process for the preparation of 1:1 metal complexes of azines of the formula ##STR1## in which R.sub.1 is an H atom or an alkyl or aryl group, R.sub.2 is an isocyclic or heterocyclic radical with a hydroxyl or mercapto group adjacent to the azomethine group, Y' is the radical of a methylene-active compound or of an aryl-or heteroaryl-amine and the ring A can have substituents which do not confer solubility in water, which comprises heating a hydrazone of the formula ##STR2## with an isoindolinone of the formula ##STR3## in which R.sub.1, R.sub.2, A and Y' are as defined, in the presence of a metal donor, in a polar organic solvent.

REFERENCES:
patent: 3974149 (1976-08-01), L'Eplattenier et al.
patent: 4022770 (1977-05-01), L'Eplattenier et al.
patent: 4366312 (1982-12-01), Iqbal

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