Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide
Patent
1981-08-07
1983-05-10
Rosen, Sam
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using tissue cell culture to make a protein or polypeptide
435 68, 435 71, C12P 2102, C12P 2104, C12P 2100
Patent
active
043830340
ABSTRACT:
The present invention relates to a process for the production of human follicle-stimulating hormone (hFSH).
More precisely, the invention relates to a process for the mass production of hFSH, comprising in vivo multiplication of human cells capable of producing hFSH, and exposure of the multiplied human cells to a follicle-stimulating hormone inducer.
The hFSH production according to the invention is much higher than that attained by conventional processes using in vitro tissue culture; thus, hFSH can be used in a sufficient amount in the prevention and treatment of human diseases.
REFERENCES:
patent: 4276282 (1981-06-01), Sugimoto et al.
patent: 4285929 (1981-08-01), Sugimoto et al.
patent: 4288546 (1981-09-01), Narasimhan et al.
patent: 4328207 (1982-05-01), Sugimoto
Chemical Abstracts, 91:86930s (1979).
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
Rosen Sam
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