Substituted imidazo 1,2-a-quinoxaline-4-(5H)ones, their composit

Details Substituted imidazo 1,2-a-quinoxaline-4-(5H)ones, their composit Substituted imidazo 1,2-a-quinoxaline-4-(5H)ones, their composit

1982-03-01

1984-10-02

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

4242484, 42424857, 424258, 544101, 544344, 544346, 544354, 544356, 546 84, A61K 31495, C07D52100

Patent

active

044747845

ABSTRACT:
Novel compounds of the formula ##STR1## wherein A is selected from the group consisting of nitrogen and .dbd.CH--, G is selected from the group consisting of --0--, ##STR2## Z is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms or taken with Y forms a carbon-nitrogen or carbon-carbon bond, Z' is selected from the group consisting of hydrogen and halogen, Y is hydrogen, or taken with Z is a carbon-nitrogen or carbon-carbon bond or taken with X is .dbd.0 and X is hydrogen or taken with Y is .dbd.0, R is selected from the group consisting of hydroxymethyl, formyl, tetrazol-5-yl, N-(tetrazol-5-yl) carbamoyl, aminomethyl and carbamoyl, R.sub.1 is selected from the group consisting of hydrogen, halogen and alkoxy of 1 to 5 carbon atoms and its non-toxic, pharmaceutically acceptable acid addition salts having anti-allergic activity and their preparation.

REFERENCES:
patent: 3706768 (1972-12-01), Bays
patent: 4075343 (1978-02-01), Kadin et al.
patent: 4145419 (1979-03-01), Rowlands et al.
patent: 4151280 (1979-04-01), Rowlands et al.
patent: 4207318 (1980-06-01), Rowlands et al.
patent: 4229452 (1980-10-01), Warner et al.

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