Treatment of cancer with phlorizin and its derivatives

Details Treatment of cancer with phlorizin and its derivatives Treatment of cancer with phlorizin and its derivatives

1987-03-18

1989-06-20

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

530370, 530395, 536 41, 536 181, 536 182, A61K 3702, C07H 100

Patent

active

048409391

ABSTRACT:
Malignant, neoplastic cells are treated by inhibiting glucose transport into the cell by administering phlorizin, phloretin or its analogs while concurrently administering adjunct therapy such as heat, radiation or chemotherapy. In this manner, the cells are prevented from growing or repairing the damage caused by the adjunct therapy, which can be administered in dosages that would otherwise be non-lethal if used alone.

REFERENCES:
patent: 3523937 (1970-08-01), Biegeleisen
patent: 4684627 (1987-08-01), Leveen et al.
Warburg, The Metabolism of Tumors, Richard R. Smith & Co., N.Y. 1931.
Warburg, Science, 123:3191, Feb. 24, 1956.
Biochemica et Biophysica Acta, 591:209, 1980.
J. Nat. Can. Inst., 62:3, Jan., 1979.
Cancer Res., 40:1699, 1980.
Cancer Res., 39:1968, 1979.
Cancer Res., 33:66, 1974.
Cancer Res., 29:391, Feb., 1969.
Cancer Res. 37:2336, 1977.
Cancer, 47:2026, 1981.
SA Med J., 59:518, 1981.
Ann NY Acad Sci, 72:103, 1980.
Science, 235:1492, Mar. 20, 1987.
J. Neurochem, 29:959, 1977.
Can. Res., 41:1165, 1981.
J. Nat. Can. Ins. 66:497, 1981.
Can. Res., 39:4242, Oct. 1979.
J. Physol 169:229, 1963.
Science, 235:1495, Mar. 20, 1987.
Harvey Lectures, 56:63, 1961.
J. Clin Invest., 12:1083, 1933.
J. Clin Invest., 13:749, 1934.
Nutri Reviews, 33:23, 1975.
Radiol. 113:209, 1974.
Radiol. 117:447, 1975.
Biochem. and Biophysica. Res. Comm. 82:787, 1978.
Cancer Res., 36:1035, 1976.
Proc. Soc. for Experimental Biology & Medicine, vol. 11, pp. 1913-1914, Benedict & Lewis.
Proc. Soc. for Experimental Biology & Medicine, vol. 11, p. 135, Wood & McLean.
Kolber et al., Chem. Abst., vol. 67, 1967, p 115099(q).
Ilinich et al., Chem. Abst., vol. 73, 1970, p 129240(q).
Nature, No. 4019, p. 663, Nov. 9, 1946.
Nature, vol. 159, p. 100, Jan. 18, 1947.
Woodcock, Chem. Abst., vol. 41, 1947, P 2859.
J. Bio. Chem., vol. 218, No. 9, p. 4978, 1972.
Physiol. Review 7, 1927, p. 385.
Physiol. Review 25, 1945, p. 255.
Z. Natureforch 36c, p. 255, 1981.
Zemplen et al., Chem Abst., vol. 36, 1942, p. 6163.
Leschbe, Chem. Abst., 1910, p. 2506.

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