Process for the preparation of 3-aminophenyl 2-hydroxy-ethyl sul

Details Process for the preparation of 3-aminophenyl 2-hydroxy-ethyl sul Process for the preparation of 3-aminophenyl 2-hydroxy-ethyl sul

1988-06-17

1990-05-29

Kight, III, John

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564305, C07C 8748, C07C14706, C07C14711, C07C 8511

Patent

active

049297570

ABSTRACT:
3-Aminophenyl 2-hydroxyethyl sulphone (I) can be prepared in a high yield and purity by treating 2-chloro-5-nitrophenyl 2-hydroxyethyl sulphone (II) or 4-chloro-3-nitrophenyl 2-hydroxyethyl sulphone (III) with hydrogen in the presence of hydrogenation catalysts in an aqueous or aqueous organic medium. (II) is obtained by reducing 2-chloro-5-nitrobenzenesulphochloride with sodium sulphite and subsequently reacting the product with ethylene oxide.

REFERENCES:
"Organosulfurchemistry", p. 692, Organic Chemistry, Allinger et al., 1971.
"Base-Catalyzed Cleavage of Epoxides", Cleavage of Epoxides, Nucleophilic Aromatic Substitution, pp. 567, 734, 826-828, Organic Chemistry, Morrison & Boyd, 1978.

Affiliated with

Also associated with

Rating

Process for the preparation of 3-aminophenyl 2-hydroxy-ethyl sul does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of 3-aminophenyl 2-hydroxy-ethyl sul, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of 3-aminophenyl 2-hydroxy-ethyl sul will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-522212